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Chicken IL1B ELISA KIT (96 T) EA800015

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Chicken IL1B ELISA KIT (96 T) EA800015

Chicken IL1B ELISA KIT (96 T)
Chicken IL-1β Immunoassay
货号：EA800015
规格：96T
品牌：OriGene
价格： ￥3200.00
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EA800015
 Product Data
DescriptionChicken IL-1β Immunoassay
Size96 T
Format96-well strip plate
Assay TypeSolid Phase Sandwich ELISA
Assay Length4 hours
SignalColorimetric
Curve Range62.5-4000pg/ml
Sample TypeSerum, plasma, Cell culture supernatant
Sample Volume100 uL
SpecificityThis assay recognizes both natural and recombinant Chicken IL-1β
Sensitivity12 pg/mL
ReactivityChicken
InterferenceNo significant interference observed with available related molecules.
Components

  • Microwell Plate - antibody coated 96-well Microplate (8 wells ×12 strips),1 plate

  • Standard - lyophilized,4000pg/ml upon reconstitution,2 vials

  • lyophilized, Biotin-Conjugated antibody,2 vials

  • Concentrated Streptavidin-HRP,1 vial

  • Standard /sample Diluent,1 bottle

  • Biotin-Conjugate antibody Diluent,1 bottle

  • Streptavidin-HRP Diluent,1 bottle

  • 20 x Wash Buffer Concentrate,1 bottle

  • Substrate Solution,1 bottle

  • Stop Solution,1 bottle

  • Plate Cover Seals,4 pieces

BackgroundInterleukin-1 beta (IL-1β) also known as catabolin, is a member of the interleukin 1 cytokine family. IL-1β precursor is cleaved by caspase 1 (interleukin 1 beta convertase). Cytosolic thiol protease cleaves the product to form mature IL-1β. Interleukin-1 alpha and interleukin-1 beta forms IL-1. IL-1β is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. IL-1β gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Gene SymbolIL1B


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